Yep - it's all I hunt in in Nova Scotia where it's frequently wet and/or cold.
Pros:
1. if you have big calves (I do. The wife says 'paint cans' but I think that's an exaggeration!) then the neoprene is snug enough around your calf that you can avoid a soaker if you go over the top of the boots, as long as you're quick about it.
2. You can roll the neoprene down to the ankle when you're driving or resting, which allows heat and moisture to escape.
3. All the pros listed in the Muckboot-love-fest above! LOL
Cons:
1. Yes, you sweat in them
2. The heel 'pocket' wears through the fabric covering of the neoprene after a while (sometimes not a very long while!). When it does, the boots become prone to causing blisters, because your sock sticks to the underlying rubber and either pulls down and/or rubs on your heel. My solution to this is when I first buy them, I wear them with thick socks. But once the heel pocket wears through the fabric, i wear them with thin socks and 'Bama Booties?, which insulate my foot, wick moisture away from my sock to the outer layer of the booties, and prevent blisters. I recommend buying them large enough to fit a thick sock or this little bootie inside.
3. The neoprene uppers are prone to tearing if your pants or chaps don't cover that part. My solution has been to buy the 'High Chore' model, which has rubber thwt extends higher up the neoprene. You can't fold them over as low, but they last longer.
Dave