I have read not until the third heat for females, but they can't get their OFA Cert. until 2 years of age. Males at a young age do not produce quality sperm. So I would wait until at least you can get all the health certs. But I am not a pro by any means, and the best way to produce the best dogs is to get as well informed as you can. I have been reading every day on this IC " Inbreed Coefficient" it is interesting and the best kennels adopt this program to produce the kind of dog they are looking for. Good Luck!!!!!!!